A sialic acid-binding lectin with bactericidal and opsonic activities from Ruditapes philippinarum
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چکیده
منابع مشابه
Sialic acid binding lectin from Rana catesbeiana oocyte
(cSBL) is known to have anti-tumor activity. cSBL is a multifunctional protein and is recognized as a pyrimidine basespecific ribonuclease. In respect to its ribonuclease activity, cSBL belongs to the RNase A superfamily, and is a very heat-stable enzyme. It retains 100% activity after heating at 100 °C for 5 min. Four RNases have been isolated from the Rana family of frogs, and their primary s...
متن کاملOpsonic function of sialic acid specific lectin in freshwater crab Paratelphusa jacquemontii
The sialic acid specific humoral lectin, Pjlec of the freshwater crab Paratelphusa jacquemontii was investigated for its opsonin function with rabbit erythrocyte as target cell for phagocytosis by the crab's hemocyte. The untreated or trypsin treated erythrocyte induced lectin response after challenge however failed when treated with neuraminidase evidently indicating glycan dependency for elic...
متن کاملVibrios isolated from the cultured manila clam (Ruditapes philippinarum): numerical taxonomy and antibacterial activities.
AIMS A numerical taxonomic study of halophilic Vibrio isolated from healthy and brown ring disease (BRD) affected manila clams (Ruditapes philippinarum), harvested from the Atlantic coast of south-western Spain, was performed. METHODS AND RESULTS Characterization of 123 presumptive Vibrio spp. was carried out using 94 phenotypic tests. Simple matching and Jaccard similarity coefficients were ...
متن کاملDetection of sialic acid on cultured cells by binding of a lectin from Limax flavus.
(J. Am. Soc. Nephrol. 1992; 3:113-1 15) washed gently in PBS and solubibized in 1 mL/wehl of 0. 1 % sodium dodecyb sulfate (BioRad, Richmond, CA), and the radioactivity was estimated with a gamma counter (LKB-Bnomma, Sweden). To study the effects of fixation, the lectin binding was measured In cells fixed in 95% ethanol. Because the fixed cells could not be solubihizcd completely in sodium dode...
متن کاملInvolvement of ER stress in apoptosis induced by sialic acid-binding lectin (leczyme) from bullfrog eggs
Sialic-acid binding lectin (SBL) isolated from bullfrog (Rana catesbeiana) oocytes is a multifunctional protein which has lectin activity, ribonuclease activity and cancer-selective antitumor activity. It has been reported that SBL induces apoptosis accompanied by rigid mitochondrial perturbation, which indicates mediation of the intrinsic pathway. However, the mechanism of the antitumor effect...
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ژورنال
عنوان ژورنال: Fish & Shellfish Immunology
سال: 2019
ISSN: 1050-4648
DOI: 10.1016/j.fsi.2019.08.074